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New march towards the regeneration of sensation and cognition: hear more, see more and learn more Free
Kejing Zhang1,†, Fei Yi1,†, Guang-Hui Liu2,*, and Juan Carlos Izpisua Belmonte1,3,*
1Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
2National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
3Center for Regenerative Medicine in Barcelona, Dr Aiguader 88, 08003 Barcelona, Spain *Correspondence to:Guang-Hui Liu, E-mail: ghliu@ibp.ac.cn; Juan Carlos Izpisua Belmonte, E-mail: belmonte@salk.edu, izpisua@cmrb.eu
J Mol Cell Biol, Volume 5, Issue 2, April 2013, 151-153,  https://doi.org/10.1093/jmcb/mjs060

As many human sensory and cognitive diseases are caused by irreversible damage or loss of certain types of neurons, methodologies aimed at replacement of lost neurons are key to restore lost sensation. Recent advances in generation of ear-cell progenitors, optic-cup structures and cortical neurons from human embryonic stem cells and induced pluripotent stem cells provide versatile tools for modeling human diseases and developing cells for replacement therapies.


Volume 5, Issue 2
April 2013